2JDS

Structure of cAMP-dependent protein kinase complexed with A-443654

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	CAMP-DEPENDENT PROTEIN KINASE	polymer	351	40917.6	1	UniProt (P00517) Pfam (PF00069)	BOS TAURUS (BOVINE)	PROTEIN KINASE A, PKA C-ALPHA
2	B (I)	CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA	polymer	20	2226.4	1	UniProt (P61925)	HOMO SAPIENS	PKI-ALPHA, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR
3	C (A)	(2S)-1-(1H-INDOL-3-YL)-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE	non-polymer		397.5	1	Chemie (L20)
4	D, E (A, I)	water	water		18.0	325	Chemie (HOH)

Sequence modifications

A: 0 - 0 (PDB: 2JDS)
A: 1 - 350 (UniProt: P00517)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	43144.0
Non-Polymers*	Number of molecules	1
	Total formula weight	397.5
All*	Total formula weight	43541.5

*Water molecules are not included.