2JCY

X-ray structure of mutant 1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXR, Rv2870c, from Mycobacterium tuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE	polymer	398	41699.0	2	UniProt (P64012) Pfam (PF02670) Pfam (PF08436) Pfam (PF13288) UniProt (by SIFTS) (P9WNS1)	MYCOBACTERIUM TUBERCULOSIS	DXP REDUCTOISOMERASE, 1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERASE, 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE SYNTHASE
2	C, D, E (A, B)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
3	F, G (A, B)	water	water		18.0	327	Chemie (HOH)

Sequence modifications

A, B: -8 - 1 (PDB: 2JCY)
A, B: 2 - 389 (UniProt: P64012)

PDB	External Database	Details
Asn 151	Asp 151	engineered mutation
Gln 222	Glu 222	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	83398.0
Non-Polymers*	Number of molecules	3
	Total formula weight	288.2
All*	Total formula weight	83686.2

*Water molecules are not included.