2JAU
Crystal structure of D41N variant of human mitochondrial 5'(3')- deoxyribonucleotidase (mdN) in complex with 3'-azidothymidine 5'- monophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 5'(3')-DEOXYRIBONUCLEOTIDASE | polymer | 197 | 22840.1 | 1 | UniProt (Q9NPB1) Pfam (PF06941) | HOMO SAPIENS (HUMAN) | 5', 3'-NUCLEOTIDASE, MITOCHONDRIAL, MITOCHONDRIAL DEOXYRIBONUCLEOTIDASE, DEOXY-5'-NUCLEOTIDASE 2, DNT-2 |
| 2 | B, E (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | C (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | D (A) | 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE | non-polymer | 347.2 | 1 | Chemie (ATM) | |||
| 5 | F (A) | water | water | 18.0 | 204 | Chemie (HOH) |
Sequence modifications
A: 32 - 228 (UniProt: Q9NPB1)
| PDB | External Database | Details |
|---|---|---|
| Asn 41 | Asp 41 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 22840.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 490.8 | |
| All* | Total formula weight | 23330.9 |
