2J95
CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ACTIVATED FACTOR XA HEAVY CHAIN | polymer | 254 | 28550.6 | 1 | UniProt (P00742) Pfam (PF00089) | HOMO SAPIENS (HUMAN) | STUART FACTOR, STUART-PROWER FACTOR |
| 2 | B (B) | ACTIVATED FACTOR XA LIGHT CHAIN | polymer | 134 | 15210.8 | 1 | UniProt (P00742) Pfam (PF00594) Pfam (PF00008) Pfam (PF14670) | HOMO SAPIENS (HUMAN) | STUART FACTOR, STUART-PROWER FACTOR |
| 3 | C (A) | 5'-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-2,2'-BITHIOPHENE-5-SULFONAMIDE | non-polymer | 504.0 | 1 | Chemie (GSX) | |||
| 4 | D (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 168 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43761.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 544.1 | |
| All* | Total formula weight | 44305.5 |
