2J90
Crystal structure of human ZIP kinase in complex with a tetracyclic pyridone inhibitor (Pyridone 6)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | DEATH-ASSOCIATED PROTEIN KINASE 3 | polymer | 304 | 35176.7 | 2 | UniProt (O43293) Pfam (PF00069) In PDB | HOMO SAPIENS (HUMAN) | DAP KINASE 3, DAP-LIKE KINASE, DLK, ZIP KINASE |
2 | A, B | 2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE | non-polymer | 309.3 | 2 | Chemie (IZA) | |||
3 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
4 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
5 | B | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
6 | water | water | 18.0 | 327 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 70353.5 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 970.8 | |
All* | Total formula weight | 71324.2 |