2J5F
Crystal structure of EGFR kinase domain in complex with an irreversible inhibitor 34-jab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | EPIDERMAL GROWTH FACTOR RECEPTOR | polymer | 327 | 37304.1 | 1 | UniProt (P00533) Pfam (PF07714) | HOMO SAPIENS (HUMAN) | RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1 |
| 2 | B (A) | N-[4-(3-BROMO-PHENYLAMINO)-QUINAZOLIN-6-YL]-ACRYLAMIDE | non-polymer | 369.2 | 1 | Chemie (DJK) | |||
| 3 | C (A) | water | water | 18.0 | 58 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37304.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 369.2 | |
| All* | Total formula weight | 37673.3 |
