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2J5E

Crystal structure of EGFR kinase domain in complex with an irreversible inhibitor 13-jab

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
EPIDERMAL GROWTH FACTOR RECEPTORpolymer32737594.41UniProt (P00533)
Pfam (PF07714)
HOMO SAPIENS (HUMAN)RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1
2B
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
3C
(A)
waterwater18.060Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight37594.4
Non-Polymers*Number of molecules1
Total formula weight35.5
All*Total formula weight37629.9
*Water molecules are not included.

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PDB entries from 2024-11-06

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