2J4Z

Structure of Aurora-2 in complex with PHA-680626

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	SERINE THREONINE-PROTEIN KINASE 6	polymer	306	35277.2	2	UniProt (O14965) Pfam (PF00069) In PDB	HOMO SAPIENS (HUMAN)	SERINE/THREONINE KINASE 15, AURORA/IPL1-RELATED KINASE 1, AURORA-RELATED KINASE 1, HARK1, AURORA-A, BREAST-TUMOR-AMPLIFIED KINASE
2	A, B	4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE	non-polymer		448.5	2	Chemie (626)
3	A, B	ARSENIC	non-polymer		74.9	3	Chemie (ARS)
4		water	water		18.0	194	Chemie (HOH)

Sequence modifications

A, B: 98 - 99 (PDB: 2J4Z)
A, B: 100 - 403 (UniProt: O14965)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	70554.4
Non-Polymers*	Number of molecules	5
	Total formula weight	1121.8
All*	Total formula weight	71676.2

*Water molecules are not included.