2J4Q
Crystal structure of a E138A Escherichia coli dCTP deaminase mutant enzyme in complex with dTTP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE | polymer | 193 | 21218.2 | 2 | UniProt (P28248) Pfam (PF00692) In PDB | ESCHERICHIA COLI | DCTP DEAMINASE |
| 2 | A | THYMIDINE-5'-DIPHOSPHATE | non-polymer | 402.2 | 1 | Chemie (TYD) | |||
| 3 | B | THYMIDINE-5'-TRIPHOSPHATE | non-polymer | 482.2 | 1 | Chemie (TTP) | |||
| 4 | B | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 193 (UniProt: P28248)
| PDB | External Database | Details |
|---|---|---|
| Ala 138 | Glu 138 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42436.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 908.7 | |
| All* | Total formula weight | 43345.1 |
