2J3Z

Crystal structure of the enzymatic component C2-I of the C2-toxin from Clostridium botulinum at pH 6.1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	C2 TOXIN COMPONENT I	polymer	431	49391.7	6	UniProt (O69275) Pfam (PF03496) In PDB	CLOSTRIDIUM BOTULINUM	ADP-RIBOSYLTRANSFERASE C2-I
2	C, F, A, D, B...	COBALT (II) ION	non-polymer		58.9	7	Chemie (CO)
3	C, F, A, D, B...	GLYCEROL	non-polymer		92.1	12	Chemie (GOL)
4	B, E, C, F, A...	SULFATE ION	non-polymer		96.1	40	Chemie (SO4)
5		water	water		18.0	592	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 431 (UniProt: O69275)

PDB	External Database	Details
Arg 77	His 77	engineered mutation
Asp 121	Asn 121	conflict

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	296350.1
Non-Polymers*	Number of molecules	59
	Total formula weight	5360.2
All*	Total formula weight	301710.3

*Water molecules are not included.