2J14

3,4,5-Trisubstituted Isoxazoles as Novel PPARdelta Agonists: Part2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA	polymer	285	32680.8	2	UniProt (Q03181) Pfam (PF00104)	HOMO SAPIENS (HUMAN)	PPAR-DELTA, PPAR-BETA, NUCLEAR HORMONE RECEPTOR 1, NUC1, NUCI, PPARDELTA
2	C, D (A, B)	(3-{4-[2-(2,4-DICHLORO-PHENOXY)-ETHYLCARBAMOYL]-5-PHENYL-ISOXAZOL-3-YL}-PHENYL)-ACETIC ACID	non-polymer		511.4	2	Chemie (GNI)
3	E, F (A, B)	water	water		18.0	129	Chemie (HOH)

Sequence modifications

A, B: 157 - 164 (PDB: 2J14)
A, B: 165 - 441 (UniProt: Q03181)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	65361.7
Non-Polymers*	Number of molecules	2
	Total formula weight	1022.7
All*	Total formula weight	66384.4

*Water molecules are not included.