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2IZT

Structure of casein kinase gamma 3 in complex with inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
CASEIN KINASE I ISOFORM GAMMA-3polymer33038557.41UniProt (Q9Y6M4)
Pfam (PF00069)
Pfam (PF12605)
HOMO SAPIENS (HUMAN)CKI-GAMMA 3, CASEIN KINASE 1 GAMMA 3
2B
(A)
N2-[(1R,2S)-2-AMINOCYCLOHEXYL]-N6-(3-CHLOROPHENYL)-9-ETHYL-9H-PURINE-2,6-DIAMINEnon-polymer385.91Chemie (23D)
3C, D
(A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
4E
(A)
waterwater18.0246Chemie (HOH)
Sequence modifications
A: 35 - 362 (UniProt: Q9Y6M4)
PDBExternal DatabaseDetails
Ser 33-expression tag
Met 34-expression tag
Ala 187Gly 187conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight38557.4
Non-Polymers*Number of molecules3
Total formula weight456.8
All*Total formula weight39014.2
*Water molecules are not included.

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PDB entries from 2025-06-11

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