2IY8
Crystal structure of the sialyltransferase PM0188 with CMP-3FNeuAc and lactose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | PROTEIN PM0188 | polymer | 389 | 45534.5 | 1 | UniProt (Q9CP67) Pfam (PF11477) In PDB | PASTEURELLA MULTOCIDA | SIALYLTRANSFERASE PM0188 |
| 2 | B | beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900004) GlyTouCan (G84224TW) | beta-lactose | ||
| 3 | A | CYTIDINE-5'-MONOPHOSPHATE-3-FLUORO-N-ACETYL-NEURAMINIC ACID | non-polymer | 632.4 | 1 | Chemie (CSF) | |||
| 4 | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A: 25 - 412 (UniProt: Q9CP67)
A: 413 - 413 (PDB: 2IY8)
| PDB | External Database | Details |
|---|---|---|
| Asn 105 | Asp 105 | conflict |
| Gln 135 | Arg 135 | conflict |
| Glu 275 | Asp 275 | conflict |
| Glu 295 | Gly 295 | conflict |
| Glu 411 | Gln 411 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45534.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 342.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 632.4 | |
| All* | Total formula weight | 46509.2 |
