2IW8

STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A F82H-L83V-H84D MUTANT WITH AN O6-CYCLOHEXYLMETHYLGUANINE INHIBITOR

Entity

Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, CCELL DIVISION PROTEIN KINASE 2polymer30234308.72
UniProt (P24941)
Pfam (PF00069)
HOMO SAPIENS (HUMAN)@PDBjCYCLIN DEPENDENT KINASE 2, P33 PROTEIN KINASE
2B, DCYCLIN-A2polymer26029884.62
UniProt (P20248)
Pfam (PF00134)
Pfam (PF02984)
HOMO SAPIENS (HUMAN)@PDBjHUMAN CYCLIN A, CYCLIN-A
3A, CO6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINEnon-polymer402.52
Chemie (4SP)
4B, DMONOTHIOGLYCEROLnon-polymer108.22
Chemie (SGM)
5waterwater18.0309
Chemie (HOH)

Sequence viewer

Contents of the asymmetric unit

PolymersNumber of chains4
Total molecular weight128386.5
Non-Polymers*Number of molecules4
Total molecular weight1021.3
All*Total molecular weight129407.8
*Water molecules are not included.
171588
PDB entries from 2020-11-25