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2IT4

X ray structure of the complex between Carbonic Anhydrase I and the phosphonate antiviral drug foscarnet

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Carbonic anhydrase 1polymer25628404.62UniProt (P00915)
Pfam (PF00194)
Homo sapiens (human)Carbonic anhydrase I, Carbonate dehydratase I, CA-I
2C, E
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
3D
(A)
PHOSPHONOFORMIC ACIDnon-polymer126.01Chemie (PPF)
4F, G
(A, B)
waterwater18.0344Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight56809.3
Non-Polymers*Number of molecules3
Total formula weight256.8
All*Total formula weight57066.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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