2ISY

Crystal structure of the nickel-activated two-domain iron-dependent regulator (IdeR)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Iron-dependent repressor ideR	polymer	157	17871.3	2	UniProt (P0A672) Pfam (PF01325) Pfam (PF02742) UniProt (by SIFTS) (P9WMH1)	Mycobacterium tuberculosis
2	C, D, F, G (A, B)	NICKEL (II) ION	non-polymer		58.7	4	Chemie (NI)
3	E, H (A, B)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
4	I, J (A, B)	water	water		18.0	148	Chemie (HOH)

Sequence modifications

A, B: 1 - 140 (UniProt: P0A672)

PDB	External Database	Details
Cso 102	Cys 102	modified residue
Ala 141	-	expression tag
Ser 142	-	expression tag
Glu 143	-	expression tag
Asn 144	-	expression tag
Leu 145	-	expression tag
Tyr 146	-	expression tag
Phe 147	-	expression tag
Gln 148	-	expression tag
Gly 149	-	expression tag
Gly 150	-	expression tag
Gly 151	-	expression tag
His 152	-	expression tag
His 153	-	expression tag
His 154	-	expression tag
His 155	-	expression tag
His 156	-	expression tag
His 157	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	35742.5
Non-Polymers*	Number of molecules	6
	Total formula weight	424.7
All*	Total formula weight	36167.2

*Water molecules are not included.