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2ISP

Ternary complex of DNA Polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-methylene triphosphate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(T)
5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'polymer164829.11
2B
(P)
5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3'polymer103045.01
3C
(D)
5'-D(P*GP*TP*CP*GP*G)-3'polymer51536.01
4D
(A)
Polymerase (DNA directed), betapolymer33538241.71UniProt (Q3KP48)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
UniProt (by SIFTS) (P06746)
Homo sapiens (human)
5E
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
6F, G, H
(A)
SODIUM IONnon-polymer23.03Chemie (NA)
7I, J, K, L, M
(A)
CHLORIDE IONnon-polymer35.55Chemie (CL)
8N
(A)
2'-DEOXY-5'-O-(HYDROXY{[HYDROXY(PHOSPHONOMETHYL)PHOSPHORYL]OXY}PHOSPHORYL)GUANOSINEnon-polymer505.21Chemie (GGH)
9O, P, Q, R
(T, P, D, A)
waterwater18.0302Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight47651.8
Non-Polymers*Number of molecules10
Total formula weight775.7
All*Total formula weight48427.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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