2ISI
Crystal structure of Ape1 from Homo sapiens in a new crystal form complexed with a ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | DNA-(apurinic or apyrimidinic site) lyase | polymer | 317 | 35475.3 | 3 | UniProt (P27695) Pfam (PF03372) | Homo sapiens (human) | AP endonuclease 1, APEX nuclease, APEN, REF-1 protein |
| 2 | D, F (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 3 | E, G, H (A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | I, J, K (A, B, C) | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 106425.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 262.9 | |
| All* | Total formula weight | 106688.7 |
