2IO3
Crystal structure of human Senp2 in complex with RanGAP1-SUMO-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sentrin-specific protease 2 | polymer | 232 | 27342.6 | 1 | UniProt (Q9HC62) Pfam (PF02902) | Homo sapiens (human) | Sentrin/SUMO-specific protease SENP2, SMT3-specific isopeptidase 2, Smt3ip2, Axam2 |
| 2 | B (B) | Small ubiquitin-related modifier 2 | polymer | 81 | 9265.4 | 1 | UniProt (P61956) Pfam (PF11976) | Homo sapiens (human) | SUMO-2, Ubiquitin-like protein SMT3B, SMT3 homolog 2, Sentrin-2, HSMT3 |
| 3 | C (C) | Ran GTPase-activating protein 1 | polymer | 172 | 18670.5 | 1 | UniProt (P46060) Pfam (PF07834) | Homo sapiens (human) |
Sequence modifications
A: 364 - 589 (UniProt: Q9HC62)
B: 15 - 93 (UniProt: P61956)
C: 418 - 587 (UniProt: P46060)
| PDB | External Database | Details |
|---|---|---|
| Gly 358 | - | cloning artifact |
| Ser 359 | - | cloning artifact |
| His 360 | - | cloning artifact |
| Met 361 | - | cloning artifact |
| Ala 362 | - | cloning artifact |
| Ser 363 | - | cloning artifact |
| Ser 548 | Cys 548 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 13 | - | cloning artifact |
| Ala 14 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Ser 416 | - | cloning artifact |
| Leu 417 | - | cloning artifact |
| Ser 573 | Cys 573 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 55278.6 | |
| All* | Total formula weight | 55278.6 |
