2IO1
Crystal structure of human Senp2 in complex with preSUMO-3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | Sentrin-specific protease 2 | polymer | 232 | 27342.6 | 3 | UniProt (Q9HC62) Pfam (PF02902) | Homo sapiens (human) | Sentrin/SUMO-specific protease SENP2, SMT3-specific isopeptidase 2, Smt3ip2, Axam2 |
| 2 | B, D, F (B, D, F) | Small ubiquitin-related modifier 3 precursor | polymer | 94 | 10589.8 | 3 | UniProt (P55854) Pfam (PF11976) | Homo sapiens (human) | SUMO-3, Ubiquitin-like protein SMT3A, SMT3 homolog 1 |
| 3 | G, H, I, J, K... (A, B, C, D, E...) | water | water | 18.0 | 278 | Chemie (HOH) |
Sequence modifications
A, C, E: 364 - 589 (UniProt: Q9HC62)
B, D, F: 14 - 103 (UniProt: P55854)
| PDB | External Database | Details |
|---|---|---|
| Gly 358 | - | cloning artifact |
| Ser 359 | - | cloning artifact |
| His 360 | - | cloning artifact |
| Met 361 | - | cloning artifact |
| Ala 362 | - | cloning artifact |
| Ser 363 | - | cloning artifact |
| Ser 548 | Cys 548 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 10 | - | cloning artifact |
| Ser 11 | - | cloning artifact |
| His 12 | - | cloning artifact |
| Met 13 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 113797.5 | |
| All* | Total formula weight | 113797.5 |
