2IMP
Crystal structure of lactaldehyde dehydrogenase from E. coli: the ternary complex with lactate (occupancy 0.5) and NADH. Crystals soaked with (L)-Lactate.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lactaldehyde dehydrogenase | polymer | 479 | 52372.5 | 1 | UniProt (P25553) Pfam (PF00171) | Escherichia coli | Aldehyde dehydrogenase A, Glycolaldehyde dehydrogenase |
| 2 | B, C (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | D (A) | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 1 | Chemie (NAI) PubChem (16219774) PubChem (928) PubChem (44119956) PubChem (44415182) PubChem (439153) PubChem (124934832) PubChem (126455899) PubChem (94865921) PubChem (94865923) PubChem (134693949) PubChem (12309339) PubChem (12309347) PubChem (124432988) PubChem (140875346) PubChem (11250888) PubChem (12309341) PubChem (124934831) PubChem (124934833) PubChem (162951601) PubChem (162951600) PubChem (164575491) PubChem (169545638) PubChem (170905224) PubChem (174316169) PubChem (129607000) PubChem (129628338) PubChem (146167236) PubChem (162951602) PubChem (174084875) | |||
| 4 | E (A) | LACTIC ACID | non-polymer | 90.1 | 1 | Chemie (LAC) PubChem (61503) PubChem (107689) PubChem (612) | |||
| 5 | F (A) | water | water | 18.0 | 221 | Chemie (HOH) |
Sequence modifications
A: 2 - 479 (UniProt: P25553)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Ocs 249 | Cys 248 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 52372.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 947.6 | |
| All* | Total formula weight | 53320.2 |
