2IIP

Human Nicotinamide N-methyltransferase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Nicotinamide N-methyltransferase	polymer	283	31466.0	4	UniProt (P40261) Pfam (PF01234)	Homo sapiens (human)
2	E, F, G, H (A, B, C, D)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	4	Chemie (SAH)
3	I, J, K, L (A, B, C, D)	water	water		18.0	285	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 264 (UniProt: P40261)

PDB	External Database	Details
Met -18	-	SEE REMARK 999
Gly -17	-	cloning artifact
Ser -16	-	cloning artifact
Ser -15	-	cloning artifact
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	cloning artifact
Ser -7	-	cloning artifact
Gly -6	-	cloning artifact
Leu -5	-	cloning artifact
Val -4	-	cloning artifact
Pro -3	-	cloning artifact
Arg -2	-	cloning artifact
Gly -1	-	cloning artifact
Ser 0	-	cloning artifact
Ala 100	Lys 100	engineered mutation
Ala 101	Glu 101	engineered mutation
Ala 103	Glu 103	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	125864.1
Non-Polymers*	Number of molecules	4
	Total formula weight	1537.6
All*	Total formula weight	127401.8

*Water molecules are not included.