2IH1
Ion selectivity in a semi-synthetic K+ channel locked in the conductive conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | FAB Heavy Chain | polymer | 219 | 23411.2 | 1 | Mus musculus (house mouse) | ||
| 2 | B (B) | FAB Light Chain | polymer | 212 | 23435.7 | 1 | Mus musculus (house mouse) | ||
| 3 | C (C) | Voltage-gated potassium channel | polymer | 122 | 13028.4 | 1 | UniProt (P0A334) Pfam (PF00520) Pfam (PF07885) | Streptomyces lividans | |
| 4 | D, E, F, G, H (C) | POTASSIUM ION | non-polymer | 39.1 | 5 | Chemie (K) | |||
| 5 | I (C) | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE | non-polymer | 442.7 | 1 | Chemie (1EM) | |||
| 6 | J, K, L (A, B, C) | water | water | 18.0 | 49 | Chemie (HOH) |
Sequence modifications
C: 3 - 122 (UniProt: P0A334)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | cloning artifact |
| Ala 2 | - | cloning artifact |
| Ala 69 | Ser 69 | engineered mutation |
| Cys 70 | Val 70 | engineered mutation |
| Dal 77 | Gly 77 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 59875.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 638.2 | |
| All* | Total formula weight | 60513.6 |
