2IG2

DIR PRIMAERSTRUKTUR DES KRISTALLISIERBAREN MONOKLONALEN IMMUNOGLOBULINS IGG1 KOL. II. AMINOSAEURESEQUENZ DER L-KETTE, LAMBDA-TYP, SUBGRUPPE I (GERMAN)

Replaces:  1IG2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (L)	IGG1-LAMBDA KOL FAB (LIGHT CHAIN)	polymer	216	22817.3	1	UniProt (P01842) Pfam (PF07654) UniProt (by SIFTS) (P0CG04)	Homo sapiens (human)
2	B (H)	IGG1-LAMBDA KOL FAB (HEAVY CHAIN)	polymer	455	49787.9	1	UniProt (P01772) Pfam (PF07686)	Homo sapiens (human)

Sequence modifications

H: 2 - 447 (UniProt: P01772)

PDB	External Database	Details
Gln 6	Glu 25	conflict
Ser 23	Ala 42	conflict
Ser 24	Ala 43	conflict
Ile 28	Thr 47	conflict
Ser 31	Asn 50	conflict
Ala 33	Gly 52	conflict
Tyr 35	His 54	conflict
Ile 50	Ala 69	conflict
Asp 53	Tyr 72	conflict
Asp 57	Asn 76	conflict
Gln 58	Lys 77	conflict
His 59	Tyr 78	conflict
Asn 73	Asp 92	conflict
Asp 74	Asn 93	conflict
Phe 80	Tyr 99	conflict
Leu 81	Met 100	conflict
Asp 84	Asn 103	conflict
Pro 88	Ala 107	conflict
Gly 92	Ala 111	conflict
Phe 95	Tyr 114	conflict
Asp 99	Glu 118	conflict
Gly 101	Arg 120	conflict
His 101	Trp 121	conflict
Gly 101	Val 122	conflict
Phe 101	Arg 123	conflict
Cys 101	Tyr 124	conflict
Ser 102	Thr 125	conflict
Ser 103	Thr 126	conflict
Ala 104	Val 127	conflict
Ser 104	Thr 128	conflict
Cys 104	Thr 129	conflict
Phe 104	Ile 130	conflict
-	Tyr 132	deletion
-	Tyr 133	deletion
Pro 105	Phe 134	conflict
Pro 113	Leu 142	conflict
Gln 153	Glu 182	conflict
Gln 273	Glu 302	conflict
Gln 284	Glu 313	conflict
Gln 295	Glu 324	conflict
Asn 313	Asp 342	conflict
Asp 316	Asn 345	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	72605.2
All*	Total formula weight	72605.2

*Water molecules are not included.