2IFD
Crystal structure of a remote binding site mutant, R492L, of CDC25B Phosphatase catalytic domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | M-phase inducer phosphatase 2 | polymer | 175 | 20637.8 | 1 | UniProt (P30305) Pfam (PF00581) In PDB | Homo sapiens (human) | Dual specificity phosphatase Cdc25B |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
A: 377 - 550 (UniProt: P30305)
| PDB | External Database | Details |
|---|---|---|
| Met 376 | - | initiating methionine |
| Leu 492 | Arg 506 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20637.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 167.0 | |
| All* | Total formula weight | 20804.7 |
