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2IE4

Structure of the Protein Phosphatase 2A Core Enzyme Bound to okadaic acid

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Protein Phosphatase 2, regulatory subunit A (PR 65), alpha isoformpolymer58965378.31UniProt (Q96DH3)
Pfam (PF02985)
UniProt (by SIFTS) (P30153)
Homo sapiens (human)Protein Phosphatase 2A
2B
(C)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoformpolymer30935636.21UniProt (P67775)
Pfam (PF00149)
Homo sapiens (human)serine/threonine protein phosphatase; PP2A-alpha; Replication protein C; RP-C
3C, D
(C)
MANGANESE (II) IONnon-polymer54.92Chemie (MN)
4E
(C)
OKADAIC ACIDnon-polymer805.01Chemie (OKA)
5F, G
(A, C)
waterwater18.064Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight101014.5
Non-Polymers*Number of molecules3
Total formula weight914.9
All*Total formula weight101929.4
*Water molecules are not included.

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