2ICV
Kinetic and Crystallographic Studies of a Redesigned Manganese-Binding Site in Cytochrome c Peroxidase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cytochrome c peroxidase, mitochondrial | polymer | 291 | 33260.9 | 1 | UniProt (P00431) Pfam (PF00141) | Saccharomyces cerevisiae (baker's yeast) | CCP |
| 2 | B (A) | COBALT (II) ION | non-polymer | 58.9 | 1 | Chemie (CO) | |||
| 3 | C (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 4 | D (A) | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
A: 4 - 294 (UniProt: P00431)
| PDB | External Database | Details |
|---|---|---|
| Glu 37 | Asp 104 | engineered mutation |
| Glu 45 | Val 112 | engineered mutation |
| Ile 53 | Thr 120 | variant |
| Gly 152 | Asp 219 | variant |
| Glu 181 | His 248 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33260.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 675.4 | |
| All* | Total formula weight | 33936.3 |
