2I78
Crystal structure of human dipeptidyl peptidase IV (DPP IV) complexed with ABT-341, a cyclohexene-constrained phenethylamine inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Dipeptidyl peptidase IV | polymer | 726 | 84252.3 | 4 | UniProt (P27487) Pfam (PF00930) Pfam (PF00326) | Homo sapiens (human) | Dipeptidyl peptidase 4, DPP IV, T-cell activation antigen CD26, TP103, Adenosine deaminase complexing protein 2, ADABP |
| 2 | E (B) | (1S,6R)-3-{[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]CARBONYL}-6-(2,4,5-TRIFLUOROPHENYL)CYCLOHEX-3-EN-1-AMINE | non-polymer | 445.4 | 1 | Chemie (KIQ) | |||
| 3 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 622 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 337009.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 445.4 | |
| All* | Total formula weight | 337454.7 |
