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2I5F

Crystal structure of the C-terminal PH domain of pleckstrin in complex with D-myo-Ins(1,2,3,5,6)P5

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Pleckstrinpolymer10912451.21UniProt (P08567)
Pfam (PF00169)
Homo sapiens (human)Platelet p47 protein
2B
(A)
(1R,2R,3R,4R,5S,6S)-6-HYDROXYCYCLOHEXANE-1,2,3,4,5-PENTAYL PENTAKIS[DIHYDROGEN (PHOSPHATE)]non-polymer580.11Chemie (5IP)
3C
(A)
waterwater18.0124Chemie (HOH)
Sequence modifications
A: 244 - 347 (UniProt: P08567)
PDBExternal DatabaseDetails
Gly 239-cloning artifact
Ser 240-cloning artifact
Phe 241-cloning artifact
Thr 242-cloning artifact
Gly 243-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight12451.2
Non-Polymers*Number of molecules1
Total formula weight580.1
All*Total formula weight13031.2
*Water molecules are not included.

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PDB entries from 2025-06-11

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