2I5C
Crystal structure of the C-terminal PH domain of pleckstrin in complex with D-myo-Ins(1,2,3,4,5)P5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Pleckstrin | polymer | 109 | 12451.2 | 3 | UniProt (P08567) Pfam (PF00169) | Homo sapiens (human) | Platelet p47 protein |
| 2 | D, E, F (A, B, C) | (1R,2S,3R,4S,5S,6R)-6-HYDROXYCYCLOHEXANE-1,2,3,4,5-PENTAYL PENTAKIS[DIHYDROGEN (PHOSPHATE)] | non-polymer | 580.1 | 3 | Chemie (IP5) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 313 | Chemie (HOH) |
Sequence modifications
A, B, C: 244 - 347 (UniProt: P08567)
| PDB | External Database | Details |
|---|---|---|
| Gly 239 | - | cloning artifact |
| Ser 240 | - | cloning artifact |
| Phe 241 | - | cloning artifact |
| Thr 242 | - | cloning artifact |
| Gly 243 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 37353.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1740.2 | |
| All* | Total formula weight | 39093.7 |
