2I4H
Structural studies of protein tyrosine phosphatase beta catalytic domain co-crystallized with a sulfamic acid inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Receptor-type tyrosine-protein phosphatase beta | polymer | 313 | 36288.0 | 1 | UniProt (P23467) Pfam (PF00102) In PDB | Homo sapiens (human) | Protein-tyrosine phosphatase beta, R-PTP-beta |
| 2 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | A | N-(TERT-BUTOXYCARBONYL)-L-TYROSYL-N-METHYL-4-(SULFOAMINO)-L-PHENYLALANINAMIDE | non-polymer | 536.6 | 1 | Chemie (UA1) | |||
| 5 | water | water | 18.0 | 182 | Chemie (HOH) |
Sequence modifications
A: 1662 - 1973 (UniProt: P23467)
| PDB | External Database | Details |
|---|---|---|
| Ser 1661 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36288.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 596.4 | |
| All* | Total formula weight | 36884.4 |
