2I40
Cdk2/Cyclin A complexed with a thiophene carboxamide inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Cell division protein kinase 2 | polymer | 298 | 33976.5 | 2 | UniProt (P24941) Pfam (PF00069) In PDB | Homo sapiens (human) | p33 protein kinase |
| 2 | B, D | Cyclin-A2 | polymer | 260 | 29867.5 | 2 | UniProt (P20248) Pfam (PF00134) Pfam (PF02984) In PDB | Homo sapiens (human) | Cyclin-A |
| 3 | A, C | 5-[5,6-BIS(METHYLOXY)-1H-BENZIMIDAZOL-1-YL]-3-{[1-(2-CHLOROPHENYL)ETHYL]OXY}-2-THIOPHENECARBOXAMIDE | non-polymer | 457.9 | 2 | Chemie (BLZ) | |||
| 4 | water | water | 18.0 | 242 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 127688.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 915.9 | |
| All* | Total formula weight | 128603.9 |
