2I08
Solvation effect in conformational changes of EF-hand proteins: X-ray structure of Ca2+-saturated double mutant Q41L-K75I of N-domain of calmodulin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Calmodulin | polymer | 78 | 8791.8 | 1 | UniProt (P62155) Pfam (PF13499) UniProt (by SIFTS) (P0DP23) | Homo sapiens (human) | CaM |
| 2 | B, C (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 3 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | E (A) | water | water | 18.0 | 50 | Chemie (HOH) |
Sequence modifications
A: 1 - 78 (UniProt: P62155)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | Ala 1 | engineered mutation |
| Tyr 19 | Phe 19 | engineered mutation |
| Leu 41 | Gln 41 | engineered mutation |
| Ile 75 | Lys 75 | engineered mutation |
| Tyr 78 | Asp 78 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 8791.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 172.3 | |
| All* | Total formula weight | 8964.1 |
