2HZN
Abl kinase domain in complex with NVP-AFG210
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proto-oncogene tyrosine-protein kinase ABL1 | polymer | 293 | 33743.5 | 1 | UniProt (Q61258) Pfam (PF07714) UniProt (by SIFTS) (P00520) | Mus musculus (house mouse) | p150, c-ABL, Abelson murine leukemia viral oncogene homolog 1 |
| 2 | B (A) | 1-[4-(PYRIDIN-4-YLOXY)PHENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA | non-polymer | 373.3 | 1 | Chemie (KIN) |
Sequence modifications
A: 229 - 515 (UniProt: Q61258)
| PDB | External Database | Details |
|---|---|---|
| Gly 223 | - | cloning artifact |
| Ala 224 | - | cloning artifact |
| Met 225 | - | cloning artifact |
| Asp 226 | - | cloning artifact |
| Pro 227 | - | cloning artifact |
| Ser 228 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33743.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 373.3 | |
| All* | Total formula weight | 34116.9 |
