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2HZ4

Abl kinase domain unligated and in complex with tetrahydrostaurosporine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Proto-oncogene tyrosine-protein kinase ABL1polymer27331678.33UniProt (P00519)
Pfam (PF07714)
Homo sapiens (human)p150, c-ABL, Abelson murine leukemia viral oncogene homolog 1
2D, E, F
(A, B, C)
1,2,3,4-TETRAHYDROGEN-STAUROSPORINEnon-polymer470.63Chemie (4ST)
3G, H, I
(A, B, C)
waterwater18.019Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight95034.8
Non-Polymers*Number of molecules3
Total formula weight1411.7
All*Total formula weight96446.5
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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