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2HZ0

Abl kinase domain in complex with NVP-AEG082

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Proto-oncogene tyrosine-protein kinase ABL1polymer27031334.02UniProt (P00519)
Pfam (PF07714)
Homo sapiens (human)p150, c-ABL, Abelson murine leukemia viral oncogene homolog 1
2C, D
(A, B)
2-{[(6-OXO-1,6-DIHYDROPYRIDIN-3-YL)METHYL]AMINO}-N-[4-PROPYL-3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDEnon-polymer429.42Chemie (GIN)
3E, F
(A, B)
waterwater18.0387Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight62667.9
Non-Polymers*Number of molecules2
Total formula weight858.9
All*Total formula weight63526.8
*Water molecules are not included.

229183

PDB entries from 2024-12-18

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