2HZ0
Abl kinase domain in complex with NVP-AEG082
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | Proto-oncogene tyrosine-protein kinase ABL1 | polymer | 270 | 31334.0 | 2 | UniProt (P00519) Pfam (PF07714) | Homo sapiens (human) | p150, c-ABL, Abelson murine leukemia viral oncogene homolog 1 |
2 | C, D (A, B) | 2-{[(6-OXO-1,6-DIHYDROPYRIDIN-3-YL)METHYL]AMINO}-N-[4-PROPYL-3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE | non-polymer | 429.4 | 2 | Chemie (GIN) | |||
3 | E, F (A, B) | water | water | 18.0 | 387 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 62667.9 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 858.9 | |
All* | Total formula weight | 63526.8 |