2HXV

Crystal structure of a diaminohydroxyphosphoribosylaminopyrimidine deaminase/ 5-amino-6-(5-phosphoribosylamino)uracil reductase (tm1828) from thermotoga maritima at 1.80 A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Diaminohydroxyphosphoribosylaminopyrimidine deaminase/ 5-amino-6-(5-phosphoribosylamino)uracil reductase	polymer	360	40667.7	1	UniProt (Q9X2E8) Pfam (PF00383) Pfam (PF01872)	Thermotoga maritima
2	B (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
3	C (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4	D (A)	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	1	Chemie (NDP)
5	E, F, G, H, I... (A)	GLYCEROL	non-polymer		92.1	8	Chemie (GOL)
6	M (A)	water	water		18.0	205	Chemie (HOH)

Sequence modifications

A: 1 - 348 (UniProt: Q9X2E8)

PDB	External Database	Details
Mse -11	-	expression tag
Gly -10	-	expression tag
Ser -9	-	expression tag
Asp -8	-	expression tag
Lys -7	-	expression tag
Ile -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Mse 1	Met 1	modified residue
Mse 6	Met 6	modified residue
Mse 53	Met 53	modified residue
Mse 183	Met 183	modified residue
Mse 342	Met 342	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	40667.7
Non-Polymers*	Number of molecules	11
	Total formula weight	1583.0
All*	Total formula weight	42250.7

*Water molecules are not included.