2HXH
KIF1A head-microtubule complex structure in adp-form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tubulin alpha chain | polymer | 451 | 50121.3 | 1 | UniProt (P02550) Pfam (PF00091) Pfam (PF03953) | Sus scrofa (pig) | |
| 2 | B (B) | Tubulin beta chain | polymer | 445 | 49907.8 | 1 | UniProt (P02554) Pfam (PF00091) Pfam (PF03953) | Sus scrofa (pig) | |
| 3 | C (C) | Kinesin-like protein KIF1A | polymer | 394 | 44302.9 | 1 | UniProt (P33173) Pfam (PF00225) | Mus musculus (house mouse) | Axonal transporter of synaptic vesicles |
| 4 | D, H (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 5 | E (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 6 | F (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 7 | G (B) | TAXOL | non-polymer | 853.9 | 1 | Chemie (TA1) PubChem (4666) PubChem (5460441) PubChem (9854162) PubChem (9897470) PubChem (10033513) PubChem (10485732) PubChem (11506104) PubChem (11828953) PubChem (14060299) PubChem (14060304) PubChem (14060306) PubChem (14060309) PubChem (15983941) PubChem (16757828) PubChem (16760674) PubChem (21458255) PubChem (23307219) PubChem (23412627) PubChem (23636632) PubChem (24848897) PubChem (24867246) PubChem (44323108) PubChem (44356961) PubChem (44403716) PubChem (46781469) PubChem (16760177) PubChem (16742549) PubChem (21733096) PubChem (23307242) PubChem (23307253) PubChem (23307913) PubChem (24754091) PubChem (24207713) PubChem (24791027) PubChem (25200067) PubChem (42613129) PubChem (42620039) PubChem (44155032) PubChem (44276363) PubChem (44279927) PubChem (44335735) PubChem (44291178) PubChem (44328863) PubChem (44342632) PubChem (44356895) PubChem (44378736) PubChem (45489039) PubChem (46782671) PubChem (71209844) PubChem (53313247) PubChem (53298534) PubChem (54259297) PubChem (54259299) PubChem (57489669) PubChem (57999380) PubChem (58460861) PubChem (58777027) PubChem (58798493) PubChem (58596717) PubChem (59048611) PubChem (59042813) PubChem (58877402) PubChem (49868078) PubChem (60005248) PubChem (59873251) PubChem (59914794) PubChem (59919147) PubChem (60123436) PubChem (60011010) PubChem (60147315) PubChem (66795656) PubChem (14060298) PubChem (176586897) PubChem (177678861) PubChem (36314) PubChem (60915) PubChem (177409) PubChem (184492) PubChem (70801836) PubChem (70842048) PubChem (70848451) PubChem (70856170) PubChem (441276) PubChem (73707502) PubChem (73759704) PubChem (89493063) PubChem (89847578) PubChem (90057663) PubChem (91122402) PubChem (91885464) PubChem (5317123) PubChem (5321715) PubChem (101920282) PubChem (5352019) PubChem (54259298) PubChem (121459571) PubChem (122361554) PubChem (6604028) PubChem (6604616) PubChem (6604814) PubChem (6713921) PubChem (6915727) PubChem (124747272) PubChem (124893098) PubChem (9875988) PubChem (126968948) PubChem (129395998) PubChem (129627423) PubChem (10748131) PubChem (132517454) PubChem (11320430) PubChem (11354895) PubChem (134368714) PubChem (134972678) PubChem (57908851) PubChem (57946364) PubChem (137705323) PubChem (138106885) PubChem (140731501) PubChem (140512017) PubChem (146034004) PubChem (58803237) PubChem (153289350) PubChem (154037993) PubChem (155982214) PubChem (159121804) PubChem (160053861) PubChem (159716711) PubChem (160171678) PubChem (160585530) PubChem (163077211) PubChem (163077212) PubChem (163077209) PubChem (163284947) PubChem (168322423) PubChem (169917882) PubChem (171036874) PubChem (175758871) PubChem (59844545) PubChem (59904698) PubChem (60123443) PubChem (70943371) PubChem (71096818) PubChem (73759783) PubChem (101598423) PubChem (118528174) PubChem (124747271) PubChem (124747273) PubChem (124747274) PubChem (126761000) PubChem (133052515) PubChem (133640187) PubChem (134715514) PubChem (143890766) PubChem (152743329) PubChem (154828192) PubChem (144453087) PubChem (160585532) PubChem (163077210) PubChem (163077213) PubChem (163077214) PubChem (163077215) PubChem (165084161) PubChem (166711459) PubChem (167423928) PubChem (170014955) PubChem (170362150) | |||
| 8 | I (C) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) |
Sequence modifications
C: 3 - 355 (UniProt: P33173)
| PDB | External Database | Details |
|---|---|---|
| Met -15 | - | cloning artifact |
| Ala -14 | - | cloning artifact |
| Ser -13 | - | cloning artifact |
| Met -12 | - | cloning artifact |
| Thr -11 | - | cloning artifact |
| Gly -10 | - | cloning artifact |
| Gly -9 | - | cloning artifact |
| Gln -8 | - | cloning artifact |
| Gln -7 | - | cloning artifact |
| Met -6 | - | cloning artifact |
| Gly -5 | - | cloning artifact |
| Arg -4 | - | cloning artifact |
| Asp -3 | - | cloning artifact |
| Pro -2 | - | cloning artifact |
| Ile -1 | - | cloning artifact |
| Asn 0 | - | cloning artifact |
| Met 1 | - | cloning artifact |
| Pro 2 | - | cloning artifact |
| Ala 202 | Pro 202 | engineered mutation |
| Asn 356 | - | linker |
| Thr 357 | - | linker |
| Val 358 | - | linker |
| Ser 359 | - | linker |
| Val 360 | - | linker |
| Asn 361 | - | linker |
| Leu 362 | - | linker |
| Glu 363 | - | linker |
| Leu 364 | - | linker |
| Thr 365 | - | linker |
| Ala 366 | - | linker |
| Glu 367 | - | linker |
| Glu 368 | - | linker |
| Trp 369 | - | linker |
| Lys 370 | - | linker |
| Lys 371 | - | linker |
| Lys 372 | - | linker |
| His 373 | - | expression tag |
| His 374 | - | expression tag |
| His 375 | - | expression tag |
| His 376 | - | expression tag |
| His 377 | - | expression tag |
| His 378 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 144331.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2296.1 | |
| All* | Total formula weight | 146628.0 |
