2HX2
Bovine eNOS heme domain complexed with (4S)-N-{4-Amino-5-[(2-aminoethyl)-hydroxyamino]-pentyl}-N'-nitroguanidine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nitric-oxide synthase | polymer | 416 | 46854.0 | 2 | UniProt (P29473) Pfam (PF02898) | Bos taurus (cattle) | EC-NOS, NOS type III, NOSIII, Endothelial NOS, eNOS, Constitutive NOS, cNOS |
| 2 | C, K (A, B) | CACODYLATE ION | non-polymer | 137.0 | 2 | Chemie (CAC) | |||
| 3 | D, E, L, M (A, B) | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 4 | F (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | G, N (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 6 | H, O (A, B) | 5,6,7,8-TETRAHYDROBIOPTERIN | non-polymer | 241.2 | 2 | Chemie (H4B) | |||
| 7 | I, P (A, B) | (4S)-N-{4-AMINO-5-[(2-AMINOETHYL)(HYDROXYAMINO]-PENTYL}-N'-NITROGUANIDINE | non-polymer | 263.3 | 2 | Chemie (3HX) | |||
| 8 | J, Q (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 9 | R, S (A, B) | water | water | 18.0 | 537 | Chemie (HOH) |
Sequence modifications
A, B: 67 - 482 (UniProt: P29473)
| PDB | External Database | Details |
|---|---|---|
| Arg 100 | Cys 99 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 93708.1 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3001.8 | |
| All* | Total formula weight | 96709.9 |
