2HW2
Crystal structure of Rifampin ADP-ribosyl transferase in complex with Rifampin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Rifampin ADP-ribosyl transferase | polymer | 143 | 15875.9 | 1 | UniProt (O67972) Pfam (PF12120) UniProt (by SIFTS) (A0QRS5) | Mycobacterium smegmatis | |
| 2 | B, C (A) | GLYCINE | non-polymer | 75.1 | 2 | Chemie (GLY) PubChem (750) | |||
| 3 | D (A) | RIFAMPICIN | non-polymer | 822.9 | 1 | Chemie (RFP) PubChem (176795423) PubChem (135403807) PubChem (135398735) PubChem (135441414) PubChem (135499655) PubChem (135484647) PubChem (135449527) PubChem (135484654) PubChem (135512673) PubChem (135671118) PubChem (135678740) PubChem (135603898) PubChem (135583296) PubChem (135762817) PubChem (135665293) PubChem (135889899) PubChem (135802250) PubChem (135887800) PubChem (135921123) PubChem (135857107) PubChem (135876149) PubChem (135887798) PubChem (135925261) PubChem (135900090) PubChem (135972658) PubChem (135928731) PubChem (136023866) PubChem (136136478) PubChem (136122621) PubChem (136170985) PubChem (136238056) PubChem (136257952) PubChem (136226255) PubChem (136254574) PubChem (136504372) PubChem (136653818) PubChem (136619758) PubChem (137007092) PubChem (136594454) PubChem (136621208) PubChem (136646928) PubChem (137097436) PubChem (137097438) PubChem (137086834) PubChem (137091153) PubChem (137108668) PubChem (137191444) PubChem (137154388) PubChem (137184359) PubChem (137154390) PubChem (137159087) PubChem (137177954) PubChem (137229761) PubChem (137222345) PubChem (137208337) PubChem (137218464) PubChem (137267378) PubChem (137286743) PubChem (137704761) PubChem (138106897) PubChem (153274061) PubChem (154075449) PubChem (155556302) PubChem (162984936) PubChem (163059759) PubChem (165729089) PubChem (171360673) PubChem (171686453) PubChem (171699545) PubChem (172916695) PubChem (172995356) PubChem (173717570) PubChem (175653389) PubChem (135476790) PubChem (135550179) PubChem (135582338) PubChem (135584810) PubChem (135665270) PubChem (135738853) PubChem (135781042) PubChem (135802251) PubChem (135814583) PubChem (135822715) PubChem (135887799) PubChem (135889901) PubChem (135915642) PubChem (135921134) PubChem (135925249) PubChem (135925741) PubChem (135932822) PubChem (136153113) PubChem (136246612) PubChem (136250494) PubChem (136257946) PubChem (136257949) PubChem (136265302) PubChem (136598085) PubChem (136601293) PubChem (136620716) PubChem (136631923) PubChem (136709103) PubChem (137016821) PubChem (137091122) PubChem (137092548) PubChem (137092933) PubChem (137097437) PubChem (137097439) PubChem (137138798) PubChem (137154389) PubChem (137154391) PubChem (137169073) PubChem (137208355) PubChem (137225336) PubChem (137229762) PubChem (137251213) PubChem (137270779) PubChem (137270910) PubChem (138756139) PubChem (162984937) PubChem (171336500) PubChem (172966639) PubChem (172987825) PubChem (173493550) | |||
| 4 | E (A) | water | water | 18.0 | 254 | Chemie (HOH) |
Sequence modifications
A: 1 - 143 (UniProt: O67972)
| PDB | External Database | Details |
|---|---|---|
| Glu 24 | Asp 24 | SEE REMARK 999 |
| Asn 46 | Lys 46 | SEE REMARK 999 |
| Ile 48 | Val 48 | SEE REMARK 999 |
| Ala 65 | Val 65 | SEE REMARK 999 |
| Phe 73 | Tyr 73 | engineered mutation |
| Ala 80 | Glu 80 | SEE REMARK 999 |
| Trp 107 | Arg 107 | SEE REMARK 999 |
| Val 116 | Glu 116 | SEE REMARK 999 |
| Pro 119 | Ser 119 | SEE REMARK 999 |
| Leu 123 | Ile 123 | SEE REMARK 999 |
| Gln 128 | Glu 128 | SEE REMARK 999 |
| Glu 132 | Asp 132 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15875.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 973.1 | |
| All* | Total formula weight | 16849.0 |
