2HVK
crystal structure of the KcsA-Fab-TBA complex in high K+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Antibody Fab heavy chain | polymer | 219 | 23411.2 | 1 | Mus musculus (house mouse) | ||
| 2 | B (B) | Antibody Fab light chain | polymer | 212 | 23435.7 | 1 | Mus musculus (house mouse) | ||
| 3 | C (C) | Voltage-gated potassium channel | polymer | 124 | 13211.6 | 1 | UniProt (P0A334) Pfam (PF00520) Pfam (PF07885) | Streptomyces lividans | |
| 4 | D (A) | NONAN-1-OL | non-polymer | 144.3 | 1 | Chemie (F09) | |||
| 5 | E, F, G, H, I... (C) | POTASSIUM ION | non-polymer | 39.1 | 6 | Chemie (K) | |||
| 6 | K (C) | (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE | non-polymer | 414.6 | 1 | Chemie (L2C) | |||
| 7 | L (C) | TETRABUTYLAMMONIUM ION | non-polymer | 242.5 | 1 | Chemie (TBA) | |||
| 8 | M, N, O (A, B, C) | water | water | 18.0 | 178 | Chemie (HOH) |
Sequence modifications
C: 1 - 124 (UniProt: P0A334)
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | Pro 2 | engineered mutation |
| Cys 90 | Leu 90 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 60058.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1035.9 | |
| All* | Total formula weight | 61094.5 |
