2HLF
Structure of the Escherichis coli ClC chloride channel Y445E mutant and Fab complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | H(+)/Cl(-) exchange transporter clcA | polymer | 444 | 47324.0 | 2 | UniProt (P37019) Pfam (PF00654) | Escherichia coli | 1EcClC H+/Cl- antiporter; ClC-ec1 |
| 2 | C, E (C, E) | Fab Fragment, Heavy chain | polymer | 221 | 23693.9 | 2 | UniProt (Q4VBH1) Pfam (PF07686) Pfam (PF07654) | Mus musculus (house mouse) | |
| 3 | D, F (D, F) | Fab Fragment, Light chain | polymer | 211 | 23088.4 | 2 | UniProt (Q58EV6) | Mus musculus (house mouse) | |
| 4 | G, H (A, B) | BROMIDE ION | non-polymer | 79.9 | 2 | Chemie (BR) |
Sequence modifications
A, B: 17 - 460 (UniProt: P37019)
| PDB | External Database | Details |
|---|---|---|
| Glu 445 | Tyr 445 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 188212.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 159.8 | |
| All* | Total formula weight | 188372.5 |
