2HKR
Structures of the carbinolamine and schiff-base intermediates in the reductive half-reaction of aromatic amine dehydrogenase (AADH) with p-methoxyphenylethylamine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (D, H) | Aromatic amine dehydrogenase, small subunit | polymer | 122 | 13469.9 | 2 | UniProt (Q0VKG6) Pfam (PF02975) UniProt (by SIFTS) (P84887) | Alcaligenes faecalis | |
| 2 | C, D (A, B) | Aromatic amine dehydrogenase, large subunit | polymer | 362 | 40113.2 | 2 | UniProt (Q0VKG7) Pfam (PF06433) UniProt (by SIFTS) (P84888) | Alcaligenes faecalis | |
| 3 | E (D) | 2-(4-METHOXYPHENYL)ETHANAMINE | non-polymer | 151.2 | 1 | Chemie (ZHH) | |||
| 4 | F (H) | 2-(4-METHOXYPHENYL)ACETAMIDE | non-polymer | 165.2 | 1 | Chemie (ZHZ) | |||
| 5 | G, H, I, J (D, H, A, B) | water | water | 18.0 | 1383 | Chemie (HOH) |
Sequence modifications
D, H: 59 - 180 (UniProt: Q0VKG6)
A, B: 72 - 432 (UniProt: Q0VKG7)
| PDB | External Database | Details |
|---|---|---|
| Trq 109 | Trp 109 | modified residue |
| PDB | External Database | Details |
|---|---|---|
| Thr 433 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 107166.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 316.4 | |
| All* | Total formula weight | 107482.6 |
