2HK9
Crystal structure of shikimate dehydrogenase from aquifex aeolicus in complex with shikimate and NADP+ at 2.2 angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Shikimate dehydrogenase | polymer | 275 | 30942.0 | 4 | UniProt (O67049) Pfam (PF08501) Pfam (PF01488) Pfam (PF18317) | Aquifex aeolicus | |
| 2 | E (A) | 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATR) | |||
| 3 | F, H, J, L (A, B, C, D) | (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID | non-polymer | 174.2 | 4 | Chemie (SKM) | |||
| 4 | G, I, K (B, C, D) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 3 | Chemie (NAP) | |||
| 5 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 204 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 269 (UniProt: O67049)
| PDB | External Database | Details |
|---|---|---|
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Glu 195 | Lys 195 | SEE REMARK 999 |
| Leu 233 | Phe 233 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 123768.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3434.0 | |
| All* | Total formula weight | 127202.1 |
