2HIJ
Crystal Structure of P14 Alanine Variant of Antithrombin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | I | Antithrombin-III | polymer | 432 | 49042.0 | 1 | UniProt (P01008) Pfam (PF00079) In PDB | Homo sapiens (human) | ATIII |
2 | L | Antithrombin-III | polymer | 432 | 49101.0 | 1 | UniProt (P01008) Pfam (PF00079) In PDB | Homo sapiens (human) | ATIII |
3 | A | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G62182OO) | |||
4 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
5 | I, L | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
6 | I, L | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
7 | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
I: 1 - 432 (UniProt: P01008)
PDB | External Database | Details |
---|---|---|
Ala 135 | Asn 167 | engineered mutation |
Ala 380 | Ser 412 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 98143.0 | |
Branched | Number of molecules | 2 |
Total formula weight | 1010.9 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1069.0 | |
All* | Total formula weight | 100223.0 |