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2HHW

ddTTP:O6-methyl-guanine pair in the polymerase active site, in the closed conformation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(E, B)
5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DDG))-3'polymer92675.82
2B, D
(F, C)
5'-D(*CP*AP*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3'polymer134030.72
3E, F
(A, D)
DNA Polymerase Ipolymer58066144.82UniProt (Q5KWC1)
Pfam (PF22619)
Pfam (PF00476)
Geobacillus stearothermophilus
4G, H
(G, H)
beta-D-fructofuranose-(2-1)-alpha-D-glucopyranosebranched342.32In PDB
BIRD (PRD_900003)
sucrose
5I, M
(A, D)
MANGANESE (II) IONnon-polymer54.92Chemie (MN)
6J, K, N
(A, D)
SULFATE IONnon-polymer96.13Chemie (SO4)
7L, O
(A, D)
2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATEnon-polymer466.22Chemie (D3T)
8P, Q, R, S, T...
(E, F, B, C, A...)
waterwater18.0794Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight145702.5
BranchedNumber of molecules2
Total formula weight684.6
Non-Polymers*Number of molecules7
Total formula weight1330.4
All*Total formula weight147717.5
*Water molecules are not included.

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PDB entries from 2025-12-10

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