2HG4

Structure of the ketosynthase-acyltransferase didomain of module 5 from DEBS.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	6-Deoxyerythronolide B Synthase	polymer	917	97980.9	6	UniProt (Q5UNP4) Pfam (PF08990) Pfam (PF00109) Pfam (PF02801) Pfam (PF16197) Pfam (PF00698) UniProt (by SIFTS) (Q03133)	Saccharopolyspora erythraea	DEBS
2	G, I, L, O, Q... (A, B, C, D, E...)	ACETATE ION	non-polymer		59.0	6	Chemie (ACT)
3	H, J, M, R, U (A, B, C, E, F)	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
4	K, N, P, S, V (B, C, D, E, F)	CHLORIDE ION	non-polymer		35.5	5	Chemie (CL)
5	AA, BA, W, X, Y... (E, F, A, B, C...)	water	water		18.0	310	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 917 (UniProt: Q5UNP4)

PDB	External Database	Details
Mse 1	Met 1	modified residue
Mse 7	Met 7	modified residue
Mse 46	Met 46	modified residue
Mse 91	Met 91	modified residue
Mse 113	Met 113	modified residue
Mse 120	Met 120	modified residue
Mse 193	Met 193	modified residue
Mse 210	Met 210	modified residue
Mse 229	Met 229	modified residue
Mse 385	Met 385	modified residue
Mse 396	Met 396	modified residue
Mse 480	Met 480	modified residue
Glu 525	Asp 525	conflict
Mse 555	Met 555	modified residue
Mse 567	Met 567	modified residue
Mse 621	Met 621	modified residue
Mse 680	Met 680	modified residue
Ala 732	Gly 732	conflict
His 733	Ile 733	conflict
Lys 734	Thr 734	conflict
Mse 786	Met 786	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	587885.5
Non-Polymers*	Number of molecules	16
	Total formula weight	1011.8
All*	Total formula weight	588897.4

*Water molecules are not included.