2HFW
Structural and kinetic analysis of proton shuttle residues in the active site of human carbonic anhydrase III
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carbonic anhydrase 3 | polymer | 260 | 29547.2 | 1 | UniProt (P07451) Pfam (PF00194) | Homo sapiens (human) | Carbonic anhydrase III, Carbonate dehydratase III, CA-III |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | water | water | 18.0 | 35 | Chemie (HOH) |
Sequence modifications
A: 1 - 260 (UniProt: P07451)
| PDB | External Database | Details |
|---|---|---|
| His 64 | Lys 63 | engineered mutation |
| Asn 67 | Arg 66 | engineered mutation |
| Ser 182 | Cys 181 | engineered mutation |
| Ser 188 | Cys 187 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29547.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 29612.6 |
