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2HE5

Crystal structure of 17alpha-hydroxysteroid dehydrogenase in binary complex with NADP(H) in an open conformation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Aldo-keto reductase family 1, member C21polymer32336924.64UniProt (Q9CX32)
Pfam (PF00248)
UniProt (by SIFTS) (Q91WR5)
Mus musculus (house mouse)
2E, F, H, K
(A, B, C, D)
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.44Chemie (NDP)
3G, J
(C, D)
ACETATE IONnon-polymer59.02Chemie (ACT)
4I
(C)
BETA-MERCAPTOETHANOLnon-polymer78.11Chemie (BME)
5L, M, N, O
(A, B, C, D)
waterwater18.0137Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight147698.3
Non-Polymers*Number of molecules7
Total formula weight3177.9
All*Total formula weight150876.2
*Water molecules are not included.

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PDB entries from 2025-06-18

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