2HDH

BIOCHEMICAL CHARACTERIZATION AND STRUCTURE DETERMINATION OF HUMAN HEART SHORT CHAIN L-3-HYDROXYACYL COA DEHYDROGENASE PROVIDE INSIGHT INTO CATALYTIC MECHANISM

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	L-3-HYDROXYACYL COA DEHYDROGENASE	polymer	293	32325.1	2	UniProt (Q16836) Pfam (PF02737) Pfam (PF00725)	Homo sapiens (human)	SCHAD
2	C, D (A, B)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
3	E, F (A, B)	water	water		18.0	253	Chemie (HOH)

Sequence modifications

A, B: 12 - 302 (UniProt: Q16836)

PDB	External Database	Details
Ala 82	Glu 84	conflict
Arg 125	Phe 137	conflict
Gln 140	His 152	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	64650.3
Non-Polymers*	Number of molecules	2
	Total formula weight	1326.8
All*	Total formula weight	65977.1

*Water molecules are not included.